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BMJ Case Rep ; 15(3)2022 Mar 24.
Article in English | MEDLINE | ID: covidwho-1765101

ABSTRACT

Thrombotic thrombocytopenic purpura (TTP) is a type of thrombotic microangiopathy that is characterized by microangiopathic haemolytic anaemia, consumption thrombocytopenia and organ injury. It is caused by a severe deficiency of ADAMTS13, which can be either congenital or acquired. There is a plethora of things that can cause the acquired form, including medications and infections. Vaccines have also been shown to cause TTP. In the midst of the COVID-19 pandemic, with multiple new vaccines being developed and distributed to the masses, the medical community needs to be aware of adverse events associated with these new vaccines. We present a case of TTP following administration of the Moderna booster vaccine.


Subject(s)
Anemia, Hemolytic , COVID-19 , Purpura, Thrombotic Thrombocytopenic , Anemia, Hemolytic/complications , COVID-19/prevention & control , Humans , Immunization, Secondary/adverse effects , Pandemics , Purpura, Thrombotic Thrombocytopenic/chemically induced , Purpura, Thrombotic Thrombocytopenic/complications
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